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Image Search Results
Journal: Cancers
Article Title: MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma Cells.
doi: 10.3390/cancers15133408
Figure Lengend Snippet: Figure 1. Interferon-γ treatment upregulates PD-L1 expression in melanoma cells, and MET inhibitors down-regulate interferon-γ induced PD-L1 expression in the melanoma cell lines. (A) Flow cytometry analysis of PD-L1 expression on the cell membrane of melanoma cells, treated with interferon-γ. Mean
Article Snippet: The
Techniques: Expressing, Flow Cytometry, Membrane
Journal: Cancers
Article Title: MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma Cells.
doi: 10.3390/cancers15133408
Figure Lengend Snippet: Figure 4. Schematic diagram of the proposed working model for the inhibition of PD-L1 by MET inhibitors in melanoma cell lines. MET inhibitors inhibit IFN-γ-induced STAT3 phosphorylation, leading to reduced PD-L1 expression and membrane presentation. IFN-γ, interferon-gamma (Created with BioRender.com: OD25HC9TFN).
Article Snippet: The
Techniques: Inhibition, Phospho-proteomics, Expressing, Membrane